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Literature summary for 3.4.24.B10 extracted from

  • McCulloch, D.R.; Harvey, M.; Herington, A.C.
    The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone (2000), Mol. Cell. Endocrinol., 167, 11-21.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
stanolone regulation in a bell-shaped, dose-dependent manner, maximal, 5fold increase in activity at 0.000001 mM Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protein + H2O Homo sapiens
-
peptides
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ALVA-41 cell androgen-dependent prostate cancer cell line Homo sapiens
-
DU-145 cell androgen-independent prostate cancer cell line Homo sapiens
-
LNCaP cell androgen-dependent prostate cancer cell line Homo sapiens
-
PC-3 cell androgen-independent prostate cancer cell line Homo sapiens
-
prostate cancer cell cell culture Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein + H2O
-
Homo sapiens peptides
-
?

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase domain 12
-
Homo sapiens
ADAM12
-
Homo sapiens
M12.212 Merops-ID Homo sapiens