Protein Variants | Comment | Organism |
---|---|---|
P475S | the common naturally occuring polymorphsim is not involved in ADAMTS13 inhibition in malaria patients | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | malaria patients possess high ADAMTS13 autoantibodies levels as well as endogenous ADAMTS13 inhibitors compared to healthy controls | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | - |
Homo sapiens | - |
plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS13 | - |
Homo sapiens |
von Willebrand factor cleaving protease | - |
Homo sapiens |
VWF cleaving protease | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor caused by Plasmodium falciparum and Plasmodium vivax malaria, overview | Homo sapiens |