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Literature summary for 3.4.24.87 extracted from
- Development of a severe von Willebrand factor/ADAMTS13 dysbalance during orthotopic liver transplantation (2009), Am. J. Transplant., 9, 1189-1196.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| von Willebrand factor + H2O | Homo sapiens | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| plasma | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| von Willebrand factor + H2O | - |
Homo sapiens | ? | - |
? | |
| von Willebrand factor + H2O | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADAMTS13 | - |
Homo sapiens |
| vWF-cleaving protease | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | development of a severe von Willebrand factor/ADAMTS13 dysbalance during orthotopic liver transplantation, overview | Homo sapiens |
| physiological function | von Willebrand factor, VWF, reactivity is regulated by a VWF-cleaving protease, ADAMTS13. A temporary ADAMTS13 deficiency during liver transplantation might contribute to postoperative thrombotic complications | Homo sapiens |
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