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Literature summary for 3.4.24.87 extracted from

  • Tao, Z.; Anthony, K.; Peng, Y.; Choi, H.; Nolasco, L.; Rice, L.; Moake, J.L.; Dong, J.F.
    Novel ADAMTS-13 mutations in an adult with delayed onset thrombotic thrombocytopenic purpura (2006), J. Thromb. Haemost., 4, 1931-1935.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HeLa cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information deletion mutation C365DEL and a point mutation R1060W severely impair ADAMTS-13 synthesis and decrease of von Willebrand cleaving activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ADAMTS-13
-
Homo sapiens
von Willebrand factor-cleaving protease
-
Homo sapiens
vWF-cleaving protease
-
Homo sapiens