Activating Compound | Comment | Organism | Structure |
---|---|---|---|
glutamate | the shedding activity of the enzyme is increased during glutamate stimulation | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DPC333 | specific inhibitor | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin-converting enzyme type 2 + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortical neuron | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin-converting enzyme type 2 + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAM17 | - |
Mus musculus |
TNF converting enzyme | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | the elevated activity of ADAM17 contributes to the glutamate-induced angiotensin-converting enzyme type 2 down-regulation | Mus musculus |