Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytochalasin D | - |
Mus musculus | |
additional information | actin cytoskeletal disruption causes endogenous activation of TACE and accumulation at the plasma membrane | Mus musculus | |
additional information | TACE activation by stimulating epithelial growth factor receptor occurs via p38/ERK | Mus musculus | |
Quinacrine | - |
Mus musculus |
Application | Comment | Organism |
---|---|---|
analysis | development of a fluorescence resonance energy transfer-based biosensor that quantitatively reports the kinetics of TACE activity in live cells | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
doxorubicin | - |
Mus musculus | |
sunitinib | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | actin cytoskeletal disruption causes endogenous activation of TACE and accumulation at the plasma membrane | Mus musculus | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9Z0F8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | embryonic fibroblast | Mus musculus | - |