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Literature summary for 3.4.24.86 extracted from

  • Canault, M.; Leroyer, A.S.; Peiretti, F.; Leseche, G.; Tedgui, A.; Bonardo, B.; Alessi, M.; Boulanger, C.M.; Nalbone, G.
    Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1 (2007), Am. J. Pathol., 171, 1713-1723.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.86

Inhibitors

Inhibitors Comment Organism Structure
TIMP-3 85% inhibition at 10 nM Homo sapiens
TMI-2 complete inhibition at 50 nM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
artery atherosclerotic plaque Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein C receptor + H2O
-
 Homo sapiens ?
-
 ?
proTNF-alpha + H2O
-
 Homo sapiens soluble TNF-alpha
-
 ?
tumour necrosis factor receptor-1 + H2O
-
 Homo sapiens ?
-
 ?
tumour necrosis factor receptor-2 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAM-17
-
 Homo sapiens
TACE
-
 Homo sapiens
TNF-alpha converting enzyme
-
 Homo sapiens
tumor necrosis factor-alpha converting enzyme
-
 Homo sapiens