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Literature summary for 3.4.24.86 extracted from

  • Moss, M.L.; White, J.M.; Lambert, M.H.; Andrews, R.C.
    TACE and other ADAM proteases as targets for drug discovery (2001), Drug Discov. Today, 6, 417-426.
    View publication on PubMed

Application

Application Comment Organism
medicine TACE as target for drug discovery, potential therapeutic target in the areas of arthritis, cancer, diabetes and HIV cachexia Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
proTNF-alpha + H2O
-
Homo sapiens soluble TNF-alpha
-
?
transforming growth factor alpha + H2O
-
Homo sapiens ?
-
?