Any feedback?
Literature summary for 3.4.24.86 extracted from
- Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4 (2000), J. Biol. Chem., 275, 10379-10387.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phorbol 12-myristate-13-acetate | - |
Mus musculus |  |
| phorbol ester | - |
Mus musculus | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cDNA encoding mouse TACE, transfection of COS-7 cells | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Mus musculus | - |
mouse | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Mus musculus | - |
| fibroblast | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| erbB4/HER4 + H2O | epidermal growth factor, essential function in heart and neural development, TACE is essential for regulated shedding of the HER4 JM-a receptor | Mus musculus | ? | - |
? | |
| proTNF-alpha + H2O | - |
Mus musculus | soluble TNF-alpha | - |
? | |
| transforming growth factor alpha + H2O | - |
Mus musculus | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
