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Literature summary for 3.4.24.85 extracted from

  • Zhang, X.; Chen, G.; Qin, C.; Wang, Y.; Wei, D.
    Slr0643, an S2P homologue, is essential for acid acclimation in the cyanobacterium Synechocystis sp. PCC 6803 (2012), Microbiology, 158, 2765-2780.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Synechocystis sp. Q55722
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-

Synonyms

Synonyms Comment Organism
Slr0643
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Synechocystis sp.

Expression

Organism Comment Expression
Synechocystis sp. wild-type displays transient induction after transfer from pH 7.5 to 6.5 up

General Information

General Information Comment Organism
physiological function gene product is essential for growth. A partially segregated mutant displays defective acid acclimation to pH 6.5. Early acid acclimation to pH 6.5 in the wild-type strain includes upregulation of sigH, hik16 and hik35 and downregulation of pcrR and sigG, as well as downregulation of porins and upregulation of inorganic carbon and nitrogen transporters. The inability of the mutant strain to survive at pH 6.5 is related to defective photosynthesis and excess expression of NADH dehydrogenase, together with excessive upregulation of carbon transporter and repression of nitrogen transporter and metabolism genes. Slr0643 disruption and expression of the sigH operon are closely related Synechocystis sp.