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Literature summary for 3.4.24.85 extracted from
- Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans (2000), Cell, 100, 391-398.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cholesterol | inhibits the first cleavage of SREBP and indirectly S2P cleavage | Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | transmembrane protein | Homo sapiens | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O43462 | s2p cloned | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa cell | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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