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Literature summary for 3.4.24.83 extracted from

  • Xie, T.; Auth, R.D.; Frucht, D.M.
    The effects of anthrax lethal toxin on host barrier function (2011), Toxins, 3, 591-607.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
mitogen-activated protein kinase kinase + H2O Bacillus anthracis
-
?
-
?

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
mitogen-activated protein kinase kinase + H2O
-
Bacillus anthracis ?
-
?

Synonyms

Synonyms Comment Organism
anthrax lethal factor
-
Bacillus anthracis
anthrax lethal toxin the pathological actions of anthrax toxin require the activities of its edema factor and lethal factor enzyme components which gain intracellular access via its receptor-binding component, protective antigen Bacillus anthracis
anthrax LF
-
Bacillus anthracis
LeTx
-
Bacillus anthracis

General Information

General Information Comment Organism
physiological function anthrax lethal toxin disrupts endothelial, intestinal epithelial, alveolar-endothelial and blood brain barriers of the host Bacillus anthracis