Protein Variants | Comment | Organism |
---|---|---|
E678C | catalytically inactive | Bacillus anthracis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | Ca2+-free medium completely prevents mitogen-activated protein kinase kinase 3 proteolysis in anthrax lethal toxin-treated macrophages | Bacillus anthracis | |
NH4Cl | blocks mitogen-activated protein kinase kinase 3 proteolysis in anthrax lethal toxin-treated macrophages | Bacillus anthracis | |
verapamil | blocks mitogen-activated protein kinase kinase 3 proteolysis in anthrax lethal toxin-treated macrophages | Bacillus anthracis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus anthracis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
mitogen-activated protein kinase kinase 1 + H2O | - |
Bacillus anthracis | ? | - |
? | |
mitogen-activated protein kinase kinase 3 + H2O | - |
Bacillus anthracis | ? | - |
? | |
additional information | participates in the activation of caspase-1 | Bacillus anthracis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lethal factor | - |
Bacillus anthracis |