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Literature summary for 3.4.24.83 extracted from
- Matrix metalloproteinase-activated anthrax lethal toxin demonstrates high potency in targeting tumor vasculature (2008), J. Biol. Chem., 283, 529-540.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| matrix metalloproteinase | matrix-metalloproteinase-activated lethal toxin has much lower in vivo toxicity than wild type toxin | Bacillus anthracis |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the antitumor toxin has potential for use in cancer therapy | Bacillus anthracis |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 89000 | - |
SDS-PAGE | Bacillus anthracis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus anthracis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| mitogen-activated protein kinase kinase + H2O | - |
Bacillus anthracis | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| anthrax lethal factor | - |
Bacillus anthracis |
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Release 2023.1 (January 2023)
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