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Literature summary for 3.4.24.83 extracted from
- Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis (2007), Cell Cycle, 6, 758-766.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | complete caspase-1 inhibition is required to block antrax lethal toxin-mediated necrosis | Bacillus anthracis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus anthracis | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| mitogen-activated protein kinase 3 + H2O | - |
Bacillus anthracis | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| anthrax lethal factor | anthrax lethal factor is part of the bipartite anthrax lethal toxin | Bacillus anthracis |
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Release 2023.1 (January 2023)
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