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Literature summary for 3.4.24.83 extracted from

  • Moayeri, M.; Robinson, T.M.; Leppla, S.H.; Karginov, V.A.
    In vivo efficacy of beta-cyclodextrin derivatives against anthrax lethal toxin (2008), Antimicrob. Agents Chemother., 52, 2239-2241.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
6-S-(3-aminopropyl)-6-thio-beta-D-cyclodextrin
-
Bacillus anthracis
6-S-(8-aminooctyl)-6-thio-beta-D-cyclodextin
-
Bacillus anthracis
6-S-[3-(aminomethyl)benzyl]-6-thio-beta-D-cyclodextrin
-
Bacillus anthracis
6-S-[4-(aminomethyl)benzyl]-6-thio-beta-D-cyclodextrin
-
Bacillus anthracis

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
-
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0003
-
-
Bacillus anthracis 6-S-(8-aminooctyl)-6-thio-beta-D-cyclodextin
0.0005
-
-
Bacillus anthracis 6-S-[3-(aminomethyl)benzyl]-6-thio-beta-D-cyclodextrin
0.0007
-
-
Bacillus anthracis 6-S-[4-(aminomethyl)benzyl]-6-thio-beta-D-cyclodextrin
0.0029
-
-
Bacillus anthracis 6-S-(3-aminopropyl)-6-thio-beta-D-cyclodextrin