Application | Comment | Organism |
---|---|---|
additional information | neurite extension mediated by the MAP kinase pathway, increased number of primary and secondary neurites | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in neurons from cerebral cortex from rats | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
E362Q | proteolytically inactive, but still activationg effect on neurite extension | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
PD98059 | inhibition of MAP kinase signaling pathway result in inhibition of neurite outgrowth induced by ADAMTS4 | Homo sapiens | |
U0126 | inhibition of MAP kinase signaling pathway result in inhibition of neurite outgrowth induced by ADAMTS4 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Homo sapiens | 9986 | - |
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O75173 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
brevican + H2O | assay at 37°C, 3 h, 25 nM recombinant ADAMTS | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS4 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |