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Literature summary for 3.4.24.82 extracted from
- Triptolide suppresses proinflammatory cytokine-induced matrix metalloproteinase and aggrecanase-1 gene expression in chondrocytes (2005), Biochem. Biophys. Res. Commun., 327, 320-327.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Tripterygium wilfordii Hook F extract | - |
Homo sapiens | |
| triptolide | 600 nM, PG490 | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| chondrocyte | - |
Homo sapiens | - |
| fibroblast | - |
Homo sapiens | - |
| SW-1353 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| aggrecan + H2O | - |
Homo sapiens | fragments of aggrecan | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| a disintegrin and metalloproteinase with thrombospondin motif | - |
Homo sapiens |
| ADAMTS4 | - |
Homo sapiens |
| aggrecanase-1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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