Literature summary for 3.4.24.81 extracted from

Hofmann, S.; V�gtle, T.; Bender, M.; Rose-John, S.; Nieswandt, B.
The SLAM family member CD84 is regulated by ADAM10 and calpain in platelets (2012), J. Thromb. Haemost., 10, 2581-2592.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O14672	-	-
Mus musculus	O35598	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood platelet	-	Homo sapiens	-
blood platelet	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CD84 + H2O	signaling lymphocyte activation molecule (SLAM) family receptor CD84	Homo sapiens	?	CD84 is cleaved from the surface of human platelets. ADAM10 is the principal sheddase responsible for CD84 cleavage	?
CD84 + H2O	signaling lymphocyte activation molecule (SLAM) family receptor CD84	Mus musculus	?	CD84 is cleaved from the surface of murine platelets. ADAM10 is the principal sheddase responsible for CD84 cleavage	?

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Release 2023.1 (January 2023)