Protein Variants | Comment | Organism |
---|---|---|
additional information | in vivo investigations of mice overexpressing either ADAM10 or dominant negative ADAM10 show unaltered cleavage of neuregulin-1 compared to wild-type animals. As a consequence, the myelin sheath thickness of peripheral nerves is unaffected in mice with altered ADAM10 activity | Mus musculus |
additional information | RNA interference (RNAi)-induced knockdown of ADAM10 in human astroglioma cell line U373 has no influence on NRG-1 (neuregulin-1) shedding | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
U-373MG cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ADAM10 | - |
Mus musculus |
ADAM10 | - |
Homo sapiens |