Literature summary for 3.4.24.81 extracted from

Schulte, M.; Reiss, K.; Lettau, M.; Maretzky, T.; Ludwig, A.; Hartmann, D.; de Strooper, B.; Janssen, O.; Saftig, P.
ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death (2007), Cell Death Differ., 14, 1040-1049.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in MEF cells and 293-T cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
AEBSF	0.1 mM	Homo sapiens
GI254023X	0.005 mM	Homo sapiens
GM6001	0.01 mM	Homo sapiens
GW280264X	0.005 mM	Homo sapiens
pepstatin A	0.001 mM	Homo sapiens
TNFalpha protease inhibitor	0.05 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Fas ligand + H2O	transmembrane protein	Homo sapiens	soluble Fas ligand ectodomain + ?	-	?

Synonyms

Synonyms	Comment	Organism
a disintegrin and metalloproteinase 10	-	Homo sapiens
ADAM10	-	Homo sapiens

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Release 2023.1 (January 2023)