Activating Compound | Comment | Organism | Structure |
---|---|---|---|
5alpha-dihydrotestosterone | 10 nM, in the presence of 10 or 50 ng/ml insulin-like growth factor, 1.8fold upregulation of the 100-kDa proform and 3 to 4 fold stimulation of the active 60-kDa form | Homo sapiens | |
Epidermal growth factor | 50 ng/ml, 2fold stimulation of 100-kDa proform and 3fold stimulation of 60-kDa form | Homo sapiens | |
insulin-like growth factor I | 10 ng/ml or 50 ng/ml, in the presence of 10 nM 5alpha-dihydrotestosterone, 1.8fold upregulation of the 100-kDa proform and 3 to 4fold stimulation of the active 60-kDa form | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
SDS-PAGE, active form of ADAM-10 | Homo sapiens |
100000 | - |
SDS-PAGE, proform of ADAM-10 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate cancer cell line | cell line LNCaP, localized to the secretory cells of prostate glands, with additional basal cell expression in benign glands | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ADAM-10 | disintegrin metalloprotease | Homo sapiens |