Literature summary for 3.4.24.81 extracted from

Gutwein, P.; Mechtersheimer, S.; Riedle, S.; Stoeck, A.; Gast, D.; Joumaa, S.; Zentgraf, H.; Fogel, M.; Altevogt, P.
ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles (2003), FASEB J., 17, 292-294.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
Golgi apparatus	most of the activity of the enzyme	Homo sapiens	5794	-
plasma membrane	some activity found	Homo sapiens	5886	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L1 adhesion molecule	Homo sapiens	ADAM10 cleaves L1	L1-200 fragment + L1-32 fragment + ?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	cell line	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
kidney cell line	wild type cell line	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L1 adhesion molecule	ADAM10 cleaves L1	Homo sapiens	L1-200 fragment + L1-32 fragment + ?	-	?

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Release 2023.1 (January 2023)