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Literature summary for 3.4.24.80 extracted from
- Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice (2009), BMC Genomics, 10, 66.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the relationship between serum MT1-MMP and bone mineral density as well as bone metabolic markers in 206 Chinese postmenopausal women aged 43-80 years is investigated by Western analysis and ELISA. Multiple linear stepwise regression analysis shows that MT1-MMP is not a determinant factor for bone mineral density. Significant positive correlations between MT1-MMP and serum alkaline phosphatase, N-telopeptides of type I collagen are found, and remain significant after adjustment for age and body-mass index. Moreover, serum MT1-MMP, BAP, and NTX decreased in response to alendronate therapy MT1-MMP and bone turnover markers are correlated, and serum MT1-MMP levels may rise with increase in bone turnover | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| serum | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MT1-MMP | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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