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Literature summary for 3.4.24.79 extracted from

  • Mueller, T.; Dieplinger, B.; Poelz, W.; Haltmayer, M.
    Increased pregnancy-associated plasma protein-A as a marker for peripheral atherosclerosis: results from the Linz Peripheral Arterial Disease Study (2006), Clin. Chem., 52, 1096-1103.
    View publication on PubMed
Search for more literature for 3.4.24.79

Application

Application Comment Organism
diagnostics increased pregnancy-associated plasma protein-A is a marker for peripheral atherosclerosis, Linz Peripheral Arterial Disease Study Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ PAPP-A is a zinc-binding metalloproteinase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens PAPP-A is involved in acute coronary syndrome, and is associated with atherosclerotic peripheral arterial disease, PAD, i.e. chronic limb ischemia, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 healthy individuals and patients with symptomatic atherosclerotic, i.e. chronic limb ischemia
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 serum PAPP-A concentrations are measured with an enzymatically amplified 2-step sandwich-type immunoassay Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PAPP-A is involved in acute coronary syndrome, and is associated with atherosclerotic peripheral arterial disease, PAD, i.e. chronic limb ischemia, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PAPP-A
-
 Homo sapiens
pregnancy-associated plasma protein-A
-
 Homo sapiens