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Literature summary for 3.4.24.79 extracted from

  • Giudice, L.C.; Conover, C.A.; Bale, L.; Faessen, G.H.; Ilg, K.; Sun, I.; Imani, B.; Suen, L.F.; Irwin, J.C.; Christiansen, M.; Overgaard, M.T.; Oxvig, C.
    Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: Evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation (2002), J. Clin. Endocrinol. Metab., 87, 2359-2366.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
IGF
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
pro-eosinophil major basic protein physiological inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens interaction between insulin-like growth factor-II and insulin-like growth factor binding protein-4 is required for proteolysis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
decidua
-
 Homo sapiens
-
trophoblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information interaction between insulin-like growth factor-II and insulin-like growth factor binding protein-4 is required for proteolysis Homo sapiens ?
-
 ?