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Literature summary for 3.4.24.74 extracted from

  • Shiryaev, S.; Remacle, A.; Chernov, A.; Golubkov, V.; Motamedchaboki, K.; Muranaka, N.; Dambacher, C.; Capek, P.; Kukreja, M.; Kozlov, I.; Perucho, M.; Cieplak, P.; Strongin, A.
    Substrate cleavage profiling suggests a distinct function of Bacteroides fragilis metalloproteinases (fragilysin and metalloproteinase II) at the microbiome-inflammation-cancer interface (2013), J. Biol. Chem., 288, 34956-34967.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.74

Protein Variants

Protein Variants Comment Organism
E349A inactive Bacteroides fragilis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 x * 25000, mature enzyme, SDS-PAGE Bacteroides fragilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
E-cadherin + H2O Bacteroides fragilis
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacteroides fragilis O86049
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AGLRRAALGG + H2O
-
 Bacteroides fragilis AGLRRAA + LGG
-
 ?
E-cadherin + H2O
-
 Bacteroides fragilis ?
-
 ?
additional information does not cleave GHSRRSRRSG Bacteroides fragilis ?
-
 ?
PTKIYDNIYD + H2O
-
 Bacteroides fragilis PTKIY + DNIYD
-
 ?
SGHMAALTA + H2O
-
 Bacteroides fragilis SGHMAA + LTA
-
 ?
SGPMSLRMTA + H2O
-
 Bacteroides fragilis SGPMSLR + MTA
-
 ?
SGPRSLKSTA + H2O
-
 Bacteroides fragilis SGPRSLK + STA
-
 ?
SGPVSMRYTA + H2O
-
 Bacteroides fragilis SGPVSMR + YTA
-
 ?

Subunits

Subunits Comment Organism
? x * 25000, mature enzyme, SDS-PAGE Bacteroides fragilis

Synonyms

Synonyms Comment Organism
FRA3 isoform Bacteroides fragilis