Literature summary for 3.4.24.74 extracted from

Kim, J.M.; Lee, D.H.; Kim, J.S.; Lee, J.Y.; Park, H.G.; Kim, Y.J.; Oh, Y.K.; Jung, H.C.; Kim, S.I.
5,7-dihydroxy-3,4,6-trimethoxyflavone inhibits the inflammatory effects induced by Bacteroides fragilis enterotoxin via dissociating the complex of heat shock protein 90 and I kappaB alpha and I kappaB kinase-gamma in intestinal epithelial cell culture (2009), Clin. Exp. Immunol., 155, 541-551.

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Inhibitors

Inhibitors	Comment	Organism	Structure
5,7-dihydroxy-3',4',6-trimethoxyflavone	inhibits the BFT induced nuclear factor-kappaB activation, interleukin-8 secretion, cyclo-oxygenase-2 expression and activated I-kappa-B-alpha and I-kappa-B-kinase signals in human colon epithelial cell line HT-29. Analysis of the mechanism of inhibition	Bacteroides fragilis

Organism

Organism	UniProt	Comment	Textmining
Bacteroides fragilis	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
Bacteroides fragilis enterotoxin	-	Bacteroides fragilis
BFT	-	Bacteroides fragilis

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Release 2023.1 (January 2023)