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Literature summary for 3.4.24.71 extracted from

  • Pacheco-Quinto, J.; Herdt, A.; Eckman, C.; Eckman, E.
    Endothelin-converting enzymes and related metalloproteases in Alzheimer's disease (2013), J. Alzheimers Dis., 33, S101.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.71

Protein Variants

Protein Variants Comment Organism
C338A the mutation in isoform ECE-1b creates a new E2F-2 transcription factor binding site and enhances expression of this intracellular isoform Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome
-
 Homo sapiens 5768
-
multivesicular body
-
 Homo sapiens 5771
-
plasma membrane
-
 Homo sapiens 5886
-
secretory vesicle
-
 Homo sapiens 99503
-
trans-Golgi network
-
 Homo sapiens 5802
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
amyloid beta peptide + H2O Homo sapiens
-
 ?
-
 ?
angiotensin I + H2O Homo sapiens
-
 ?
-
 ?
big endothelin + H2O Homo sapiens
-
 endothelin + ?
-
 ?
bradykinin + H2O Homo sapiens
-
 ?
-
 ?
neurotensin + H2O Homo sapiens
-
 ?
-
 ?
somatostatin + H2O Homo sapiens
-
 ?
-
 ?
Substance P + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P42892
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid beta peptide + H2O
-
 Homo sapiens ?
-
 ?
angiotensin I + H2O
-
 Homo sapiens ?
-
 ?
big endothelin + H2O
-
 Homo sapiens endothelin + ?
-
 ?
bradykinin + H2O
-
 Homo sapiens ?
-
 ?
neurotensin + H2O
-
 Homo sapiens ?
-
 ?
somatostatin + H2O
-
 Homo sapiens ?
-
 ?
Substance P + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ECE-1
-
 Homo sapiens
ECE-1b isoform Homo sapiens