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Literature summary for 3.4.24.7 extracted from

  • Wooley, D.E.; Tucker, J.S.; Green, G.; Evanson, J.M.
    A neutral collagenase from human gastric mucosa (1976), Biochem. J., 153, 119-126.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
Homo sapiens
alpha2-Macroglobulin
-
Homo sapiens
Cys
-
Homo sapiens
dithiothreitol
-
Homo sapiens
EDTA
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastric mucosa
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O
-
Homo sapiens ? two collagen fragments representing 77% and 23% respectively of the length of the collagen molecule ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8.5
-
Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
6.5 9.5 pH 6.5: about 65% of maximal activity, pH 9.5: about 60% of maximal activity Homo sapiens