Application | Comment | Organism |
---|---|---|
analysis | generation of specific recombinant human monoclonal antibody SP1, which may serve as building block for the development of antibody-based therapy strategies in mouse models of pathology | Mus musculus |
Cloned (Comment) | Organism |
---|---|
recombinant expression of His-tagged isolated MMP-1 catalytic domain as soluble cytoplasmic protein in Escherichia coli | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of specific recombinant human monoclonal antibody SP3, which is specific to the murine MMP-1 catalytic domain | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | a zinc-containing endopeptidase | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
Sv129 mice | - |
Mus musculus Sv129 | - |
Sv129 mice | - |
Purification (Comment) | Organism |
---|---|
recombinant His-tagged isolated MMP-1A catalytic domain by nickel affinity chromatography from Escherichia coli | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | MMP-1A is strongly expressed in tumor and arthritis specimens, expression patterns of MMP-1A in a variety of healthy, cancerous and arthritic murine tissues, overview | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 + H2O | fluorogenic substrate | Mus musculus | ? | - |
? | |
Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 + H2O | fluorogenic substrate | Mus musculus Sv129 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | MMP-1A comprises a signal peptide and a propeptide, a catalytic domain and a hemopexin-like domain | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase 1 | - |
Mus musculus |
MMP-1A | - |
Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
assay at | Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | MMP-1A is strongly expressed in tumor and arthritis specimens | Mus musculus |