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Literature summary for 3.4.24.69 extracted from
- Differential endopeptidase activity of different forms of type A botulinum neurotoxin A unique relationship between the size of the substrate and activity of the enzyme (2018), Toxicon, 144, 34-41 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Clostridium botulinum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| synaptosome-associated protein SNAP-25 + H2O | Clostridium botulinum | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium botulinum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Clostridium botulinum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the reduction of the disulfide bond is necessary for the optimum activity of the enzyme | Clostridium botulinum | ? | - |
? | |
| SNAPtide 520 + H2O | - |
Clostridium botulinum | ? | - |
? | |
| synaptosome-associated protein SNAP-25 + H2O | - |
Clostridium botulinum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BoNT/A | - |
Clostridium botulinum |
| type A botulinum neurotoxin | - |
Clostridium botulinum |
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Release 2023.1 (January 2023)
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