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Literature summary for 3.4.24.69 extracted from

  • Liu, Q.; Sinnen, B.L.; Boxer, E.E.; Schneider, M.W.; Grybko, M.J.; Buchta, W.C.; Gibson, E.S.; Wysoczynski, C.L.; Ford, C.P.; Gottschalk, A.; Aoto, J.; Tucker, C.L.; Kennedy, M.J.
    A photoactivatable botulinum neurotoxin for inducible control of neurotransmission (2019), Neuron, 101, 863-875.e6 .
    View publication on PubMedView publication on EuropePMC
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General Stability

General Stability Organism
targeting the enzyme to vesicles improves its efficacy Clostridium botulinum

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ dependent on Clostridium botulinum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
vesicle-associated membrane protein-2 + H2O Clostridium botulinum
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium botulinum P10844
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
vesicle-associated membrane protein-2 + H2O
-
 Clostridium botulinum ?
-
 ?

Subunits

Subunits Comment Organism
? x * 50000, light chain subunit of botulinum neurotoxin B, SDS-PAGE Clostridium botulinum

Synonyms

Synonyms Comment Organism
BoNT/B
-
 Clostridium botulinum
BoNT/B-LC light chain subunit of botulinum neurotoxin B Clostridium botulinum
botulinum neurotoxin B
-
 Clostridium botulinum