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Literature summary for 3.4.24.69 extracted from
- Substrate recognition strategy for botulinum neurotoxin serotype A (2004), Nature, 432, 925-929.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| complex of botulinum neurotoxin serotype A protease bound to human SNAP-25, 2.1 A resolution | Clostridium botulinum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium botulinum | - |
serotype A | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| synaptosome-associated protein SNAP-25 + H2O | significant structural changes near the toxin's catalytic pocket upon substrate binding, probably serving to render the protease competent for catalysis | Clostridium botulinum | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| botulinum neurotoxin serotype A | - |
Clostridium botulinum |
| CNT endopeptidase | - |
Clostridium botulinum |
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