Activating Compound | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum | |
goat serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum | |
horse serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum | |
Human serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum | |
additional information | stimulation specific to serum albumins, bovine gamma globulin, ovalbumin, lysozyme, ribonuclease, and gelatin have no effect | Clostridium botulinum | |
rabbit serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum | |
sheep serum albumin | stimulates hydrolysis of synthetic peptides | Clostridium botulinum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.58 | - |
SNKTRIDEANQRATKXL | pH 7.3, 37°C | Clostridium botulinum | |
0.6 | - |
SNKTRIDEAAQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
0.75 | - |
SNKTRIDQANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
0.75 | - |
SNKTRIDEANNRATKML | pH 7.3, 37°C | Clostridium botulinum | |
0.82 | - |
SNKTRINEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
0.83 | - |
SNKTRIDEANBRATKML | pH 7.3, 37°C | Clostridium botulinum | |
0.9 | - |
SNKTRIDEANQRATK | pH 7.3, 37°C | Clostridium botulinum | |
1 | - |
SNKTRIDEANQRATAML | pH 7.3, 37°C | Clostridium botulinum | |
1.1 | - |
SNKTRIDEBNQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
1.2 | - |
SNKTRIDEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
1.3 | - |
SNKTRIDEANQRABKML | pH 7.3, 37°C | Clostridium botulinum | |
1.6 | - |
SNKTRIDEANQRATKM | pH 7.3, 37°C | Clostridium botulinum | |
1.7 | - |
SNKTRIDEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
1.8 | - |
SNKTRIDEANQRBTKML | pH 7.3, 37°C | Clostridium botulinum | |
1.9 | - |
SNKTRIDEANQRATKAL | pH 7.3, 37°C | Clostridium botulinum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc-dependent endoproteinase | Clostridium botulinum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Clostridium botulinum | most potent toxin known | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium botulinum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | most potent toxin known | Clostridium botulinum | ? | - |
? | |
neuronal proteinSNAP-25 + H2O | - |
Clostridium botulinum | ? | - |
? | |
SNKTRIDEAAQRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEAAQ + RATKML | - |
? | |
SNKTRIDEANBRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANB + RATKML | - |
? | |
SNKTRIDEANNRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANN + RATKML | - |
? | |
SNKTRIDEANQRABKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RABKML | - |
? | |
SNKTRIDEANQRASKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RASKML | - |
? | |
SNKTRIDEANQRATAML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATAML | - |
? | |
SNKTRIDEANQRATK + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATK | - |
? | |
SNKTRIDEANQRATKAL + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATKAL | - |
? | |
SNKTRIDEANQRATKM + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATKM | - |
? | |
SNKTRIDEANQRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATKML | - |
? | |
SNKTRIDEANQRATKXL + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RATKXL | - |
? | |
SNKTRIDEANQRBTKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEANQ + RBTKML | - |
? | |
SNKTRIDEBNQRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRIDEBNQ + RATKML | - |
? | |
SNKTRIDQANQRATKML + H2O | - |
Clostridium botulinum | ? | - |
? | |
SNKTRINEAAQRATKML + H2O | synthetic peptide substrate | Clostridium botulinum | SNKTRINEAAQ + RATKML | - |
? | |
SNKTRINEANQRATKML + H2O | - |
Clostridium botulinum | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
botox A | - |
Clostridium botulinum |
type A botulinum neurotoxin | - |
Clostridium botulinum |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1 | - |
SNKTRIDEANQRATK | pH 7.3, 37°C | Clostridium botulinum | |
1.8 | - |
SNKTRIDEAAQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
5 | - |
SNKTRINEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
7.7 | - |
SNKTRIDEANBRATKML | pH 7.3, 37°C | Clostridium botulinum | |
8 | - |
SNKTRIDEANQRATAML | pH 7.3, 37°C | Clostridium botulinum | |
9 | - |
SNKTRIDEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
11 | - |
SNKTRIDEBNQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
19 | - |
SNKTRIDEANNRATKML | pH 7.3, 37°C | Clostridium botulinum | |
25 | - |
SNKTRIDEANQRATKAL | pH 7.3, 37°C | Clostridium botulinum | |
30 | - |
SNKTRIDEANQRATKXL | pH 7.3, 37°C | Clostridium botulinum | |
35 | - |
SNKTRIDEANQRABKML | pH 7.3, 37°C | Clostridium botulinum | |
39 | - |
SNKTRIDEANQRBTKML | pH 7.3, 37°C | Clostridium botulinum | |
47 | - |
SNKTRIDEANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
51 | - |
SNKTRIDQANQRATKML | pH 7.3, 37°C | Clostridium botulinum | |
56 | - |
SNKTRIDEANQRATKM | pH 7.3, 37°C | Clostridium botulinum |