Literature summary for 3.4.24.69 extracted from

Saathyamoorthy, V.; DasGupta, B.R.
Separation, purification, partial characterization and comparison of the heavy and light chains of botulinum neurotoxin types A, B, and E (1985), J. Biol. Chem., 260, 10461-10466.

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Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
additional information	-	comparison of amino acid sequences of H- and L-chains of serotypes A, B and E	Clostridium botulinum
additional information	-	amino acid content	Clostridium botulinum
50000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
51000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
53000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
97000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
102000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
104000	-	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
150000	-	Clostridium botulinum, serotype BoNT/A, SDS-PAGE, calculated from amino acid sequence	Clostridium botulinum
152000	-	Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence	Clostridium botulinum
155000	-	Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence	Clostridium botulinum

Organism

Organism	UniProt	Comment	Textmining
Clostridium botulinum	-	serotypes BoNT/A, BoNT/B	-
Clostridium botulinum	-	BoNT/E	-

Purification (Commentary)

Purification (Comment)	Organism
serotypes BoNT/A, B, E (and their H-chain and L-chain)	Clostridium botulinum
serotypes BoNT/A, B, E, C, D, F	Clostridium botulinum

Subunits

Subunits	Comment	Organism
dimer	1 * 50000 + 1 * 102000, Clostridium botulinum, serotype BoNT/E, calculated from amino acid sequence, 1 * 51000 + 1 * 104000, Clostridium botulinum, serotype BoNT/B, calculated from amino acid sequence, 1 * 53000 + 1 * 97000, Clostridium botulinum, serotype BoNT/A, calculated from amino acid sequence	Clostridium botulinum
More	serotype BoNT/E: single-chain polypeptide, serotype BoNT/B: mixture of single- and 2-chain molecules, serotype BoNT/A: 2-chain molecule	Clostridium botulinum

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Release 2023.1 (January 2023)