Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | geldanamycin efficiently blocks the neurotoxic activity of the enzyme. The interchain disulfide of the enzyme can be specifically reduced by incubating the enzyme with NADPH, thioredoxin and thioredoxin reductase. Reduced enzyme is not toxic | Clostridium tetani |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
vesicle associated membrane protein + H2O | Clostridium tetani | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium tetani | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
vesicle associated membrane protein + H2O | - |
Clostridium tetani | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TeNT | - |
Clostridium tetani |
Tetanus neurotoxin | - |
Clostridium tetani |