Literature summary for 3.4.24.64 extracted from

Nagayama, K.; Itono, S.; Yoshida, T.; Ishiguro, S.; Ochiai, H.; Ohmachi, T.
Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins (2008), Biosci. Biotechnol. Biochem., 72, 1836-1846.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of beta subunit of MPP mRNA is down-regulated during early development, the level of the beta subunit of MPP protein is constant throughout the life cycle	Dictyostelium discoideum

Inhibitors

Inhibitors	Comment	Organism	Structure
antisense RNA	transformants expressing the anti-sense RNA of the beta subunit of MPP: beta subunit of MPP protein increases about 1.8-fold relative to the wild type, and its mRNA increases 4.5-fold, expression of alpha subunit also increases. Results indicate that expression is induced by the antisense RNA of the MPP's beta subunit gene	Dictyostelium discoideum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrial matrix	beta and alpha subunit of MPP, Western blot of the mitochondrial subfractions	Dictyostelium discoideum	5759	-
mitochondrial membrane	beta subunit of MPP, not alpha subunit of MPP, Western blot of the mitochondrial subfractions	Dictyostelium discoideum	31966	-

Organism

Organism	UniProt	Comment	Textmining
Dictyostelium discoideum	-	-	-

Subunits

Subunits	Comment	Organism
heterodimer	alphaMPP and betaMPP	Dictyostelium discoideum

Synonyms

Synonyms	Comment	Organism
mitochondrial processing peptidase	-	Dictyostelium discoideum
MPP	-	Dictyostelium discoideum

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Release 2023.1 (January 2023)