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Literature summary for 3.4.24.64 extracted from

  • Waltner, M.; Weiner, H.
    Conversion of a nonprocessed mitochondrial precursor protein into one that is processed by the mitochondrial processing peptidase (1995), J. Biol. Chem., 270, 26311-26317.
    View publication on PubMed
Search for more literature for 3.4.24.64

Inhibitors

Inhibitors Comment Organism Structure
3-Oxoacyl-CoA thiolase signal peptide weak, cytochrome c oxidase subunit IV as substrate Rattus norvegicus
Aldehyde dehydrogenase precursor peptide cytochrome c oxidase subunit IV as substrate Rattus norvegicus
Linker-deleted aldehyde dehydrogenase signal peptide weak, cytochrome c oxidase subunit IV as substrate Rattus norvegicus
additional information glucagon, bovine serum albumin, rabbit reticulocyte lysate Rattus norvegicus
Rhodanese cytochrome c oxidase subunit IV as substrate Rattus norvegicus
Rhodanese signal peptide
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Aldehyde dehydrogenase precursor + H2O
-
 Rattus norvegicus ?
-
 ?
Cytochrome c oxidase subunit IV precursor + H2O
-
 Rattus norvegicus Cytochrome c oxidase subunit IV
-
 ?
additional information thiolase with added R-3 MPP recognition site, rhodanese with RPG-linker (i.e. 3 amino acid linker of aldehyde dehydrogenase precursor), linker deleted aldehyde dehydrogenase Rattus norvegicus ?
-
 ?
additional information No substrates are mitochondrial matrix proteins lacking cleavable signal sequences, e.g. 3-oxoacyl-CoA thiolase, rhodanese Rattus norvegicus ?
-
 ?
additional information substrate recognition specificity Rattus norvegicus ?
-
 ?
Rhodanese with added MPP recognition site + H2O i.e. R-3 site: Xaa-Arg-Xaa-Tyr-+-Ser/Ala, added after residue 22 of rhodanese, processed to a lesser extent than native precursor proteins, the term-+- depicts the point of cleavage Rattus norvegicus ?
-
 ?
RPG-Rhodanese with added MPP recognition site + H2O i.e. R-3 site: Xaa-Arg-Xaa-Tyr-+-Ser/Ala, added after residue 22 of rhodanese, processed to a lesser extent than native precursor proteins, the term-+- depicts the point of cleavage Rattus norvegicus ?
-
 ?