Cloned (Comment) | Organism |
---|---|
rat (MPP1 polypeptide) | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | excess Mn2+ restores | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
soluble | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | requirement | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
1 * 52000 + 1 * 55000, SDS-PAGE | Rattus norvegicus |
55000 | - |
1 * 52000 + 1 * 55000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | removes amino-terminal matrix-targeting sequences from imported mitochondrial precursor proteins during or after translocation across mitochondrial membranes | ? | - |
? | |
additional information | Rattus norvegicus | polypeptides destined to be imported from cytosol into mitochondrial matrix or inner mitochondrial membrane, critical step in the import of nuclear encoded precursor proteins into mitochondria | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
More | - |
homology between rat, yeast and Neurospora enzymes | - |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
2 components, a catalytically active MW 55000 and a MW 52000 subunit in a 1:1 ratio | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | removes amino-terminal matrix-targeting sequences from imported mitochondrial precursor proteins during or after translocation across mitochondrial membranes | Rattus norvegicus | ? | - |
? | |
additional information | polypeptides destined to be imported from cytosol into mitochondrial matrix or inner mitochondrial membrane, critical step in the import of nuclear encoded precursor proteins into mitochondria | Rattus norvegicus | ? | - |
? | |
MPPI precursor + H2O | MPPI presumably takes part in its own precursor activation | Rattus norvegicus | MPPI | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 52000 + 1 * 55000, SDS-PAGE | Rattus norvegicus |