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BRENDA support

Literature summary for 3.4.24.62 extracted from

  • Guillou, M.D.; Camier, M.; Clamagirand, C.
    Evidence for the presence of pro-oxytocin/neurophysin-converting enzyme in the human ovary (1994), J. Endocrinol., 142, 345-352.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Homo sapiens
additional information no inhibition by PMSF, pepstatin Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
secretory granule
-
Homo sapiens 30141
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
human Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Pro-oxytocin/neurophysin + H2O Homo sapiens involved in post-translational processing ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
corpus luteum
-
Homo sapiens
-
ovary granulosa cells and follicular fluid Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Pro-oxytocin/neurophysin + H2O involved in post-translational processing Homo sapiens ?
-
?
Pro-oxytocin/neurophysin(1-20) + H2O strictly selective for basic amino acid doublet Lys11-Arg12, cleavage site: Arg12-Ala13 Homo sapiens Pro-oxytocin/neurophysin(1-12) + pro-oxytocin/neurophysin(13-20) i.e. peptide II (i.e. oxytocinGly10Lys11Arg12 and peptide III) ?