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Literature summary for 3.4.24.59 extracted from

  • Pena-Diaz, P.; Mach, J.; Kriegova, E.; Poliak, P.; Tachezy, J.; Lukes, J.
    Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase (2018), PLoS ONE, 13, e0196474 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.59

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion the enzyme displays an exclusively mitochondrial localization Trypanosoma brucei 5739
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Organism

Organism UniProt Comment Textmining
Trypanosoma brucei Q389Z4
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Source Tissue

Source Tissue Comment Organism Textmining
procyclic form
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 Trypanosoma brucei
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Synonyms

Synonyms Comment Organism
MIP
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 Trypanosoma brucei

General Information

General Information Comment Organism
malfunction down-regulation of the putative Trypanosoma brucei mitochondrial intermediate peptidase (MIP) homolog by RNAi renders the cells unable to grow after 48 hours of induction. Ablation of MIP results in the accumulation of the precursor of the trypanosomatid-specific trCOIV protein, the largest nuclear-encoded subunit of the cytochrome c oxidase complex in this flagellate Trypanosoma brucei