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Literature summary for 3.4.24.59 extracted from

  • Isaya, G.; Kalousek, F.
    Mitochondrial intermediate peptidase (1995), Methods Enzymol., 248, 556-567.
    View publication on PubMed
Search for more literature for 3.4.24.59

Cloned(Commentary)

Cloned (Comment) Organism
-
 Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Co2+ 1 mM Rattus norvegicus
EDTA
-
 Rattus norvegicus
Fe2+ 1 mM Rattus norvegicus
iodoacetamide
-
 Rattus norvegicus
iodoacetic acid
-
 Rattus norvegicus
NEM
-
 Rattus norvegicus
p-hydroxymercuribenzoate
-
 Rattus norvegicus
Synthetic peptides
-
 Rattus norvegicus
Thiol-blocking reagents
-
 Rattus norvegicus
Zn2+ 1 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial matrix
-
 Rattus norvegicus 5759
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 1 mM, stimulates 2.2fold Rattus norvegicus
Mg2+ 1 mM, stimulates 4.8fold Rattus norvegicus
Mn2+ 1 mM, stimulates 4.5fold Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
 1 * 75000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-70°C, stable for at least 6 months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Mitochondrial intermediate proteins + H2O with the amino-terminal octapeptide Phe/Ile/Leu-Xaa-Xaa-Ser/Thr/Gly-Xaa-Xaa-Xaa-Xaa Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 75000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.6 8.9
-
 Rattus norvegicus