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Literature summary for 3.4.24.57 extracted from

  • van der Wal, D.E.; DU, V.X.; Lo, K.S.; Rasmussen, J.T.; Verhoef, S.; Akkerman, J.W.
    Platelet apoptosis by cold-induced glycoprotein Ibalpha clustering (2010), J. Thromb. Haemost., 8, 2554-2562.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycoprotein Ibalpha + H2O extracellular GPIbalpha is removed by O-sialoglycoprotein endopeptidase treatment Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
O-sialoglycoprotein endopeptidase
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Homo sapiens

General Information

General Information Comment Organism
physiological function GPIbalpha-clustering activates caspase-9 activation and phosphatidylserine surface expression. This is opposed by O-sialoglycoprotein endopeptidase treatment Homo sapiens