Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc metallopeptidase | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
islet amyloid polypeptide + H2O | Mus musculus | degradation of islet amyloid polypeptide in beta-cells | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8K411 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
islet amyloid polypeptide + H2O | degradation of islet amyloid polypeptide in beta-cells | Mus musculus | ? | - |
? | |
islet amyloid polypeptide + H2O | degradation of monomeric, but not oligomeric islet amyloid polypeptide in vitro | Mus musculus | ? | - |
? |
General Information | Comment | Organism |
---|---|---|
metabolism | overexpression of pitrilysin protects insulinoma cells from human islet amyloid polypeptide-induced apoptosis | Mus musculus |