Literature summary for 3.4.24.56 extracted from

Udrisar, D.P.; Wanderley, M.I.; Porto, R.C.; Cardoso, C.L.; Barbosa, M.C.; Camberos, M.C.; Cresto, J.C.
Androgen- and estrogen-dependent regulation of insulin-degrading enzyme in subcellular fractions of rat prostate and uterus (2005), Exp. Biol. Med., 230, 479-486.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Rattus norvegicus	enzyme may participate in prostatic and uterine growth	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
prostate gland	activity and amount of enzyme decrease in the cytosolic fraction with castration and increase with testpsterone treatment	Rattus norvegicus	-
uterus	activity and amount of enzyme decrease during metestrus and increase with estradiol treatment and proestrus	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme may participate in prostatic and uterine growth	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)