Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bacitracin | - |
Drosophila melanogaster | |
additional information | not: aprotinin; not: pancreatic trypsin inhibitor | Drosophila melanogaster | |
NEM | - |
Drosophila melanogaster | |
PCMB | - |
Drosophila melanogaster |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000003 | - |
Insulin | procine substrate | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Drosophila melanogaster | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
Drosophila melanogaster, gel filtration | Drosophila melanogaster |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
insulin + H2O | Drosophila melanogaster | important role in the metabolism of insulin | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
Kc cells | - |
Purification (Comment) | Organism |
---|---|
- |
Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Kc cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Insulin + H2O | not: individual A and B-chains of insulin | Drosophila melanogaster | Hydrolyzed insulin | - |
? | |
Insulin + H2O | equine | Drosophila melanogaster | Hydrolyzed insulin | - |
? | |
insulin + H2O | important role in the metabolism of insulin | Drosophila melanogaster | ? | - |
? | |
Insulin growth factor II + H2O | - |
Drosophila melanogaster | ? | - |
? | |
additional information | insulin-like growth factor I | Drosophila melanogaster | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 110000, Drosophila melanogaster, SDS-PAGE | Drosophila melanogaster |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Drosophila melanogaster |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | - |
Drosophila melanogaster |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.5 | pH 6.5: about 30% of activity maximum, pH 8.5: about 60% of activity maximum | Drosophila melanogaster |