Literature summary for 3.4.24.56 extracted from

Duckworth, W.C.; Hamel, F.G.; Bennett, R.; Ryan, M.P.; Roth, R.A.
Human red blood cell insulin-degrading enzyme and rat skeletal muscle insulin protease share antigenic sites and generate identical products from insulin (1990), J. Biol. Chem., 265, 2984-2987.

Search for more literature for 3.4.24.56

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	chelator-treated enzyme can be reactivated by Ca2+	Homo sapiens
Ca2+	chelator-treated enzyme can be reactivated by Ca2+	Rattus norvegicus
Mn2+	chelator-treated enzyme can be reactivated by Mn2+	Homo sapiens
Mn2+	chelator-treated enzyme can be reactivated by Mn2+	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
110000	-	x * 110000, human, SDS-PAGE	Homo sapiens
110000	-	x * 110000, human, SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens
-	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-
skeletal muscle	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Insulin + H2O	-	Homo sapiens	Hydrolyzed insulin	-	?
Insulin + H2O	-	Rattus norvegicus	Hydrolyzed insulin	-	?

Subunits

Subunits	Comment	Organism
?	x * 110000, human, SDS-PAGE	Homo sapiens
?	x * 110000, human, SDS-PAGE	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)