Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Crotalus atrox | |
EDTA | - |
Crotalus atrox | |
Hemorrhagic toxin inhibitor from Crotalus atrox | - |
Crotalus atrox |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc metalloproteinase, 1 mol zinc/mol enzyme | Crotalus atrox |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | - |
1 * 24000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crotalus atrox | - |
Western diamondback rattlesnake | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Crotalus atrox | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Basement membrane preparation + H2O | poor substrate: component band a | Crotalus atrox | Soluble peptides | - |
? | |
Laminin + H2O | basement membrane component, poor substrate | Crotalus atrox | ? | - |
? | |
additional information | no hydrolysis of fibrin | Crotalus atrox | ? | - |
? | |
additional information | no hydrolysis of fibronectin | Crotalus atrox | ? | - |
? | |
Nidogen + H2O | basement membrane component | Crotalus atrox | ? | - |
? | |
Oxidized insulin B-chain + H2O | cleavage sites: His5-Leu6, His10-Leu11, Ala14-Leu15, Tyr16-Leu17 (atrolysin A and C cleave the same bonds) and Gly23-Phe24 (atrolysin C, EC 3.4.24.42 cleaves the same bond) | Crotalus atrox | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 24000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Crotalus atrox |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0267 | - |
oxidized insulin B-chain | Gly23-Phe24 bond | Crotalus atrox | |
0.0317 | - |
oxidized insulin B-chain | His5-Leu6 bond | Crotalus atrox | |
0.132 | - |
oxidized insulin B-chain | His10-Leu11 bond | Crotalus atrox | |
0.803 | - |
oxidized insulin B-chain | Ala14-Leu15 bond | Crotalus atrox | |
1.02 | - |
oxidized insulin B-chain | Tyr16-Leu17 bond | Crotalus atrox |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
basic pI | Crotalus atrox |