Cloned (Comment) | Organism |
---|---|
- |
Crotalus atrox |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Crotalus atrox | |
EDTA | - |
Crotalus atrox | |
Hemorrhagic toxin inhibitor from Crotalus atrox | - |
Crotalus atrox |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc metalloproteinase, 1 mol zinc/mol enzyme | Crotalus atrox |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | - |
1 * 24000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Basement membranes surrounding capillaries + H2O | Crotalus atrox | involved in disruption of capillary membranes, together with atrolysins C and E member of the class P-I hemorrhagic toxins, most abundant hemorrhagic toxin in the venom | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crotalus atrox | - |
Western diamondback rattlesnake | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | no glycoprotein | Crotalus atrox |
Purification (Comment) | Organism |
---|---|
from lyophilized crude venom | Crotalus atrox |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Crotalus atrox | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Basement membrane preparation + H2O | - |
Crotalus atrox | Soluble peptides | - |
? | |
Basement membranes surrounding capillaries + H2O | involved in disruption of capillary membranes, together with atrolysins C and E member of the class P-I hemorrhagic toxins, most abundant hemorrhagic toxin in the venom | Crotalus atrox | ? | - |
? | |
Fibrinogen + H2O | - |
Crotalus atrox | Hydrolyzed fibrinogen | - |
? | |
Laminin + H2O | - |
Crotalus atrox | ? | - |
? | |
additional information | no hydrolysis of fibrin | Crotalus atrox | ? | - |
? | |
additional information | possesses hemorrhagic, proteolytic and myonecrotic activity | Crotalus atrox | ? | - |
? | |
Nidogen + H2O | basement membrane component | Crotalus atrox | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 24000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pI: 8.2, estimated from amino acid sequence | Crotalus atrox |